教　授　　多田　茂

教授

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一　言

　当研究室は、本科応用物理学科・研究科境界科学専攻の中で生命科学系の研究室です。

　バイオエンジニアリング(生体工学)の研究活動、知見の修得に関心のある方は是非当研究室にお越しください。


所　属

　防衛大学校　応用科学群　応用物理学科


連絡先

　電　話：046-841-3810 (代表)

　メール：stada＠nda.ac.jp ※＠は半角に置き換えてください

　居　室：防衛大学校　理工学２号館１階　145号室

専門分野

　生体流体力学

　生体熱物質輸送

学　歴

　1987.3　東京工業大学 工学部 機械工学科 卒業

　1989.3　東京工業大学大学院 理工学研究科 機械工学専攻 修士課程 修了

　1992.3　同 博士後期課程 修了 博士(工学)

職　歴

　1992. 4-1992. 9
： ㈶鉄道総合技術研究所 研究員
　1992.10-1996. 8
： 東京工業大学 工学部 機械工学科 助手
　1996. 9-1997. 8
： Pennsylvania State University 客員研究員
　1997. 9-2007. 3
： 東京工業大学 工学部 機械工学科 助手
　2007. 4-2011. 3
： 防衛大学校 准教授
　2011. 4-
： 防衛大学校 教　授

担当講義

　物理学(専門基礎)

　連続体力学

研究業績 (刊行論文)

  1. Shigeru Tada: Computational Study of the Influence of Bifurcation Angle on Haemodynamics and Oxygen Transport in the Carotid Bifurcation, Biomedical Engineering: Applications, Basis and Communications, Vol.31, No.3, pp.1950024-1-1950024-8, 2019.
  2. Shigeru Tada, Masanori Eguchi, Kohei Okano: Insulator-based Dielectrophoresis Combined with the Isomotive AC Electric Field and Applied to Single Cell Analysis, Electrophoresis, Vol.40, pp.1494–1497, 2019.
  3. Megumi Baba, Aya Shinmura, Shigeru Tada, Taku Amo, Akira Tsukamoto: Mitochondrial Remodeling in Endothelial Cells Under Cyclic Stretch Is Independent of Drp1 Activation, Molecular & Cellular Biomechanics, Vol.16, No.1, pp.1-12, 2019.
  4. Toru Takahashi, Keiichi Nakagawa, Shigeru Tada, Akira Tsukamoto: Low-energy Shock Waves Evoke Intracellular Ca2+ Increases Independently of Sonoporation, Scientific Reports, Vol.9, No.1, 3218, 2019.
  5. Shigeru Tada, Yui Omi, Masanori Eguchi: Analysis of the Dielectrophoretic Properties of Cells Using the Isomotive AC Electric Field, Biomicrofluidics, Vol.12, No.4, pp.044103-1-044103-12, 2018.
  6. Shigeru Tada, Masako Hayashi, Masanori Eguchi, Akira Tsukamoto: High-throughput Separation of Cells by Dielectrophoresis Enhanced with 3D Gradient AC Electric Field, Biomicrofluidics, Vol.11, No.6, pp.064110-1-064110-14, 2017.
  7. Shigeru Tada, Yan Shen, Zhiyong Qiu: Modeling and Simulation of Dielectrophoretic Collective Dynamics in a Suspension of Polarizable Particles Under the Action of a Gradient AC Electric Field, Electrophoresis, Vol.38, No.9, pp.1434-1440, 2017.
  8. Shigeru Tada, Zhiyong Qiu, Yan Shen: Concentration-tuned Interactions and Structures in Flowing Suspensions Under a Gradient AC Electric Field, Journal of Applied Physics, Vol.120, No.17, pp.174505-1-174505-11, 2016.
  9. Shiegru Tada, Arisa Nakanishi, Masanori Eguchi, Keigo Ochi, Megumi Baba, Akira Tsukamoto: Enhancement of Continuous-flow Separation of Viable/nonviable Yeast Cells Using a Nonuniform Alternating Current Electric Field with Complex Spatial Distribution, Biomicrofluidics, Vol.10, No.4, pp.034110-1-034110-14, 2016.
  10. Masanari Hirahara, Akira Tsukamoto, Hiroki Goto, Shigeru Tada, Masayuki Yagi, Yasushi Umemura: Visible-light-Induced Morphological Changes of Giant Vesicles by Photoisomerization of a Ruthenium Aqua Complex, Chemistry - A European Journal, Vol.22, No.3, pp.2590-2594, 2016.
  11. Koji Toriyama, Shigeru Tada, Koichi Ichimiya, Shumpei Funatani, Yosuke Tomita: A New Method of Temperature Measurement Using Thermochromic Liquid Crystals (Extension of Measurable Range Based on Spectral Intensity in the Narrow-Band Wavelength), International Journal of Heat & Mass Transfer, Vol.92, pp.483-489, 2016.
  12. 鳥山孝司, 多田茂, 一宮浩市, 舩谷俊平, 冨田洋佑: 感温液晶を用いた温度計測法の計測可能温度範囲の拡張 (狭帯域波長スペクトル強度に注目した方法), 日本機械学会論文集, Vol.81, No.830, 15-00090, 2015.
  13. Aya Shinmura, Akira Tsukamoto, Tsuyoshi Hamada, Kouki Takemura, Takashi Ushida, Shigeru Tada: Morphological Dynamics of Mitochondria in Bovine Aortic Endothelial Cell Under Cyclic Stretch, Advanced Biomedical Engineering, Vol.4, pp.60-66, 2015.
  14. Shigeru Tada, Tomoyuki Natsuya, Akira Tsukamoto: Numerical Simulation of Dielectrophoretic Separation of Live/Dead Cells Using a Three-dimensional Nonuniform AC Electric Field in Micro-Fabricated Devices, Biorheology, Vol.52, No.3, pp.211-224, 2015.
  15. Shigeru Tada, Tomoyuki Natsuya, Akira Tsukamoto: Dielectric Aggregation Kinetics of Cells in a Uniform AC Electric Field, Biorheology, Vol.51, No.6, pp.381-397, 2015.
  16. 鳥山孝司, 多田茂, 一宮浩市, 舩谷俊平: 感温液晶を用いた非接触温度分布計測技術, Chemical Engineering, Vol.59, No.3, pp.202-207, 2014.
  17. Shigeru Tada, Tomoyuki Natsuya, Akira Tsukamoto, Yudai Santo: Contactless Cell Trapping by the Use of a Uniform AC Electric Field, Biorheology, Vol.50, No5, pp.283-303, 2013.
  18. 藤田貴行, 塚本哲, 多田茂: 第1次自己回帰過程の重ね合わせモデルによる平均血圧変動ゆらぎの解析, 日本機械学会論文集C編, Vol.79, No.802, pp.1980-1989, 2013.
  19. Shigeru Tada: Treatment of Quantum Zero Point Energy Constraint in Simulations of Molecular Dynamics, Engineering Computations, Vol.28, No.4, pp.508-523, 2011.
  20. 藤田貴行, 塚本哲, 多田茂: 第一次自己回帰モデルによるゆらぎの解析, 日本機械学会論文集C編, Vol.77, No.780, pp.3017-3024, 2011.
  21. Shigeru Tada, Yan Shen, David Jacqmin, Bingmei Fu, Zhiyong Qiu: Understanding Electric Interactions in Suspensions in Gradient AC Electric Fields II - Simulations and Application, International Journal of Modern Physics B, Vol.25, No.7, pp.927-933, 2011.
  22. Yan Shen, Zhiyong Qiu, Shigeru Tada: Understanding Electric Interactions in Suspensions in Gradient AC Electric Fields I - Experimental, International Journal of Modern Physics B, Vol.25, No.7, pp.919-925, 2011.
  23. Shigeru Tada, Hirokazu Ozono: Computational Study of LDL Mass Transport in the Artery Wall, Journal of Biorheology, Vol.25, No.1-2, pp.27-35, 2011.
  24. Shigeru Tada: Numerical Study of Oxygen Transport in a Carotid Bifurcation, Physics in Medicine and Biology, Vol.55, No.14, pp.3993-4010, 2010.
  25. 多田　茂, John M. Tarbell: 頸動脈分岐部の幾何形状が動脈壁面酸素輸送に与える影響, 日本機械学会論文集, 第76巻, 772号B編, pp.2127-2134, 2010.
  26. Takashi Ichiya, Nobuki Koiwa, Atsushi Ohma, Shigeru Tada, Kazuyoshi Fushinobu and Ken Okazaki: Surface Electronic/Atomic Structure and Activation Energy on Pt(111), Pt3Cu(111) and PtCu(111) for PEFC Cathode, Nanoscale & Microscale Thermophysical Engineering, Vol.14, No.2, pp.110-122, 2010.
  27. Shigeru Tada, Satoshi Akiyama: Modeling of Mechanosensitive Channel Gating in Response to Wall Shear Stress, Journal of Biorheology, Vol. 23, pp.87-94, 2009.
  28. Shigeru Tada, Koichi Ichimiya: Numerical Simulation of Forced Convection in Porous Circular Tube with Constant Wall Heat Flux - Extended Graetz Problem with Viscous Dissipation, Chemical Engineering & Technology, Vol.30, No.10, pp.1362-1368, 2007.
  29. Shigeru Tada, Koichi Ichimiya: Analysis of Laminar Dissipative Flow and Heat Transfer in a Porous Saturated Circular Tube with Constant Wall Heat Flux, International Journal of Heat & Mass Transfer, 50, 11-12, p2406-2413, 2007.
  30. 多田　茂, John M. Tarbell: 頸動脈分岐部での流れの数値解析 (分岐部幾何形状・流量比とWSS分布との関係), 日本機械学会論文集, 第73巻, 728号B編, pp.930-935, 2007.
  31. Shigeru Tada, Cheng Dong and John M. Tarbell: Effect of the Stress Phase Angle (SPA) on the Strain Energy Density of the Endothelial Plasma Membrane, Biophysical Journal, Vol.93, No.9, pp.3026-3033, 2007.
  32. Shigeru Tada, Ken, Okazaki: A Novel Single-Photon Counting Technique Applied to Highly Sensitive Measurement of [Ca2+]i Transient in Human Aortic Smooth Muscle Cells, Transactions of ASME Journal of Biomechanical Engineering, Vol.128, pp.777-781, 2006.
  33. Shigeru Tada, John M. Tarbell: Oxygen Mass Transport in a Compliant Carotid Bifurcation Model, Annals of Biomedical Engineering, Vol.34, No.9, pp.1389-1399, 2006.
  34. Shigeru Tada, John M. Tarbell: A Computational Study of Flow in a Compliant Carotid Bifurcation – Stress Phase Angle Correlation with Shear Stress, Annals of Biomedical Engineering, Vol.33, No.9, pp.1202-1212, 2005.
  35. Shigeru Tada, John M. Tarbell: Internal Elastic Lamina Affects the Distribution of Macromolecules in the Arterial Wall - A Computational Study, American Journal of Physiology, Vol.287, H905-H913, 2004.
  36. Shigeru Tada, John M. Tarbell: Flow Through Internal Elastic Lamina Affects Shear Stress on Smooth Muscle Cells (3D Simulation), American Journal of Physiology, Vol.282: H576-H584, 2002.
  37. Shigeru Tada, John M. Tarbell: Fenestral Pore Size in the Internal Elastic Lamina Affects Transmural Flow Distribution in the Artery Wall, Annals of Biomedical Engineering, Vol.29, No.6, pp.456-466, 2001.
  38. Shigeru Tada, John M. Tarbell: Interstitial Flow Through the Internal Elastic Lamina Affects Shear Stress on Arterial Smooth Muscle Cells, American Journal of Physiology, Vol.278: H1589-H1597, 2000.
  39. Hideo Yoshida, Kenichi, P. Kobayashi, Shigeru Tada, Kazuhiro Higuchi, Takashi Nozaki, Ryozo Echigo: Response of Low- and High-speed Streaks to Injection or Suction in a Minimal Flow Unit, Turbulence and Shear Flow Phenomena, Vol.1, pp.1333-1338, 1999.
  40. 多田 茂, 吉田英生, 越後亮三，大石安志: CAES-G/T地下空洞の熱的挙動の数値予測, 日本機械学会論文集 第64, 627号B編, pp.3830-3837, 1998.
  41. Shigeru Tada, Ryozo Echigo, Hideo Yoshida: Numerical Analysis of Electromagnetic Wave in a Partially Loaded Microwave Applicator, International Journal of Heat & Mass Transfer, Vol.41, No.5, pp.709-718, 1998.
  42. 多田 茂, 壁谷尚樹, 吉田英生, 越後亮三: 電気粘性流体の流体力学的特性に関する基礎的研究, 日本機械学会論文集 第63巻, 613号B編, pp.2985-2992, 1997.
  43. J.G.Hoffmann, R.Echigo, H.Yoshida, S.Tada: Experimental Study on Combustion in Porous Media with a Reciprocating Flow System, Combustions and Flame, Vol.111, pp.32-46, 1997.
  44. Shigeru Tada, Shuzo Oshima, Ryuichiro Yamane: Flow Patterns in Curved Pipes, Transactions of ASME Journal of Biomechanical Engineering, Vol.118, pp.311-317, 1996.
  45. Tomoyuki Sugiyama, Ryozo Echigo, Hideo Yoshida, Shigeru Tada: Inversion Mechanism of Joule-Thomson Effect, Thermal Science & Engineering, Vol.2, No.1, pp.125-131 1994.
  46. Shigeru Tada, Yasushi Fukui, Shuzo Oshima, Ryuichiro Yamane: Effects of Bingham Viscosity on Flow in Curved Pipes, JSME International Journal Series B, Vol.37, pp.322-327, 1994.
  47. 杉山智之, 越後亮三, 吉田英生: 多田 茂: ジュール・トムソン効果の反転機構, 日本機械学会論文集, 第60巻, 573号B編, pp.1683-1689, 1994.
  48. 多田 茂, 大島修造, 山根隆一郎: 曲がり管内脈動流における拡散効果, 日本機械学会論文集, 第58巻, 551号B編, pp.2074-2079, 1992.
  49. 多田 茂, 大島修造, 山根隆一郎: 曲がり管内脈動流におけるビンガム流体の流動特性(べき乗則モデルを用いた近似解析), 日本機械学会論文集, 第58巻, 547号B編, pp.672-679, 1992.
  50. 多田 茂, 大島修造, 山根隆一郎: 曲がり管内脈動流におけるビンガム流体の流動特性(実験ならびに数値解析による検討), 日本機械学会論文集, 第58巻, 546号B編, pp.349-355, 1992.
  51. 多田 茂, 大島修造, 山根隆一郎: 曲がり管内定常流におけるビンガム流体の流動特性(数値解析による検討), 日本機械学会論文集, 57巻, 542号B編, pp.3333-3339, 1991.
  52. 多田 茂, 福井康嗣, 大島修造, 山根隆一郎: 曲がり管内流れにおけるビンガム粘性の効果, 日本機械学会論文集, 第57巻, 541号B編, pp.2956-2961, 1991.
  53. 多田 茂, 大島修造, 山根隆一郎: 曲がり管内過渡流れにおける流体のビンガム性の効果, ターボ機械協会誌, 19巻, 8号, pp.461-467, 1991.
  54. 多田 茂, 大島修造, 山根隆一郎: テンソルの物理成分を用いた曲がり管内振動流の数値解析, 日本機械学会論文集, 第57巻, 536号B編, pp.1257-1264, 1991.
  55. 多田 茂, 大島修造, 山根隆一郎: 曲がり管内脈動流におけるLyne型渦の発生限界, 日本機械学会論文集, 第56巻, 532号B編, pp.3611-3616, 1990.
  56. 多田 茂, 大島修造, 山根隆一郎: 曲がり管内脈動流の流動パターン, 日本機械学会論文集, 第56巻, 531号B編, pp.3240-3247, 1990.
  57. 多田 茂, 持丸義弘: 圧力こう配法の自然対流問題への適用, 1989, 日本機械学会論文集, 第55巻, 513号B編, pp.1329-1333, 1989.

研究業績 (国際会議)

  1. Noriko Sato, Shigeru Tada, Masanori Eguchi: Estimation of Electric Properties of Mammalian Cells Using the Creek-gap Dielectrophoretic Electrode, The 10th Asian-Pacific Conference on Biomechanics, Taipei, Taiwan, 2019.
  2. Daisuke Kokui, Koji Toriyama, Shigeru Tada, Koichi Ichimiya, Shumpei Funatani: Temperature Distribution Measurement Using Ratio of Scattered Light Intensities from Thermo-chromic Liquid Crystal: Uncertainty Evaluation, 16th International Heat Transfer Conference, 24087, Beijing, China, 2018.
  3. Shigeru Tada, Yui Omi, Masanori Eguchi, Noriko Nakai, Akira Tsukamoto: Analysis of Dielectrophoretic Properties of Cells by the Use of the Uniform Field Gradient, Proceedings of World Automation Congress 2018, IFMIP TP-1-3, Washington, U.S.A., 2018.
  4. Koji Toriyama, Shigeru Tada, Koichi Ichimiya, Shumpei Funatani, Keisuke Asano, Effects of the Type of TLCs for Measureable Temperature Range of Temperature Distribution Measurement Method Using Ratio of Scattered Light Intensities, The Ninth JSME-KSME Thermal & Fluids Engineering Conference, Okinawa, Japan, 2017.
  5. Megumi Baba, Akira Tukamoto, Toru Takahashi，Keiichi Nakagawa, Shigeru Tada: Remodeling of Actin Cytoskeletons Induced by Low-energy Shock Wave Irradiation, The 16th International Conference on Biomedical Engineering, Singapore, 2016
  6. Toru Takahashi, Akira Tsukamoto, Keiichi Nakagawa, Shigeru Tada: Intracellular Ca2+ Increase in Endothelial Cells Induced by Shock Wave Irradiation, 5th Joint Meeting of the Acoustical Society of America and Acoustical Society of Japan, Honolulu, Hawaii, U.S.A., 2016
  7. Megumi Baba, Akira Tukamoto, Toru Takahashi, Shigeru Tada: Mitochondria Alteration Induced by Shock Wave Irradiation, Japan-US Forum on Blast Injury 2016, U.S. Naval　Joint Services Activity, Tokyo, Japan, 2016.
  8. Toru Takahashi, Akira Tsukamoto, Shigeru Tada: Shock Wave Irradiations Avoiding Fluid Flow Evoke Intracellular Ca2+ Signaling, APS March Meeting 2016, Baltimore, U.S.A.
  9. Megumi Baba, Aya Shinmura, Koki Takemura, Keigo Shimizu, Taku Amou, Akira Tsukamoto, Shigeru Tada: Mitochondria Dynamics in Human Aortic Endothelial Cells under Supra-physiologic Level Cyclic Stretches, ASBC Annual Meeting 2015, San Diego, U.S.A., 2015.
  10. Toru Takahashi, Akira Tsukamoto, Keiichi Nakagawa, Takashi Ushida, Shigeru Tada: Momentum Transfer from Propagating Shock Waves to Single Cells, The 8th Asian-Pacific Conference on Biomechanics, PS2-15, Sapporo, Japan, 2015.
  11. Megumi Baba, Akira Tsukamoto, Aya Shinmura, Koki Takemura, Taku Amou, Takashi Ushida, Shigeru Tada: Mitochondria Dynamics in Human Aortic Endothelial Cells under Supra-physiologic Level Cyclic Stretches, The 8th Asian-Pacific Conference on Biomechanics, PS2-16, Sapporo, Japan, 2015.
  12. Shigeru Tada: Separation of Live/Dead Cells by the Use of Three Dimensional Non-uniform AC Electric Field, Proceedings of World Automation Congress, Hawaii, U.S.A., 2014.
  13. Takayuki Fujita, Akira Tsukamoto, Shigeru Tada: 1/f Noises as a Superposition of First Order Autoregressive Model, American Physical Society March Meeting 2012, Boston, U.S.A., 2012.
  14. Yan Shen, Shigeru Tada, Zhiyong Qiu: Effects of Memories of Polarization Interactions during Particle Transport Induced by One Gradient AC Electric Field, Technical Proceedings of the 2009 NSTI Nanotechnology Conference, Vol.3, pp.537-540, Texas, U.S.A., 2009.
  15. Zhiyong Qiu, Shigeru Tada, Yan Shen: Concentration Tuned Interactions and Structures in One Gradient AC Electric Field, Technical Proceedings of the 2009 NSTI Nanotechnology Conference, Vol.3, pp.509-512, Texas, U.S.A., 2009.
  16. Shiegru Tada, Yan Shen, Zhiyong Qiu: External Field Induced Non-Uniform Growth of Micron Composite Materials in Insulating Liquid: Experimental and Simulation, Technical Proceedings of the 2008 NSTI Nanotechnology Conference, Vol.3, pp.390-393，Boston, U.S.A., 2008.
  17. Zhiyong Qiu, Yan Shen, Shigeru Tada, David Jacqmin: Micron Particles Segregation in Lower Electric Field Regions in Very Dilute Neutrally Buoyant Suspensions, Technical Proceedings of the 2008 NSTI Nanotechnology Conference, Vol.3, pp.308-311, Boston, U.S.A., 2008.
  18. Su. Wang, R. Sharma, Shigeru Tada, John, M. Tarbell: Effects of Flow on Vascular Smooth Muscle Cells, Summer Bioengineering Conference in Big Sky, Montana U.S.A., 2000.
  19. Shigeru Tada, Hideo Yoshida, Ryozo Echigo, Yasushi Oishi: A Numerical Study on the Thermal Behavior of a Cavern for the CAES-G/T, The ASME/JSME Thermal Engineering Joint Conference, San Diego, U.S.A., 1999.
  20. Hideo Yoshida, Shigeru Tada, Yasushi Oishi, Takahiro Hatoya, Ryozo Echigo, Cho-Young Hang: Thermo-fluid Behavior in the Cavern for the Compressed Air Energy Storage Gas Turbine System, The 11th International Heat Transfer Conference, Kyongju, Korea, 1998.
  21. Shigeru Tada, Ryozo Echigo, Hideo Yoshida: A New Concept of Porous Thermoelectric Module Using a Reciprocating Flow for Cooling/Heating System -Numerical Analysis for Heating System, The 16th International Conference on Thermoelectrics, Dresden, Germany, 1997.
  22. Juergen Hoffmann, Ryozo Echigo, Shigeru Tada, Hideo Yoshida: Analytical Study on Flame Stabilization in Reciprocating Combustion in Porous Media with High Thermal Conductivity, The 26th Symposium on Combustion, Naples, Italy, 1996.
  23. Jurgen Hoffmann, Ryozo Echigo, Shigeru Tada, Hideo Yoshida: Analytical Study on Flammable Limit of Reciprocating Superadiabatic Combustion in Porous Media, The 8th ISTP, California, U.S.A., 1996.
  24. Shigeru Tada, Ryozo Echigo, Hideo Yoshida: A New Concept of Porous Thermoelectric Module Using a Reciprocating Flow for Heating System, Proceedings of the 14th International Conference on Thermoelectrics, pp.264-268, Yokohama, Japan, 1996
  25. Ryozo Echigo, Kiyoshi Tawata, Hideo Yoshida, Shigeru Tada: Effective Heating/Cooling Method for Porous Thermoelectric Devicein Reciprocating Flow Combustion System, ASME/JSME Joint Conference, Hawaii U.S.A., 1995.
  26. Shigeru Tada, Shuzo Oshima and Ryuichiro Yamane: Flow Patterns of the Fully Developed Pulsatile Flow in a Curved Pipe, The Proceedings of the 2nd KSME-JSME Fluids Engineering Conference, 2, II-332-II-337, Seoul, Korea, 1991.

研究室の業績

その他の活動（学外）

所属学会：

　日本機械学会、日本流体力学会、日本レオロジー学会、日本バイレオロジー学会、日本心脈管作動物質学会