Given the increased likelihood of deployment of Japan Self-Defense Forces abroad for international contribution and peacekeeping missions, the threat to these forces from a variety of diseases not experienced in Japan has become an area of concern. Ebola hemorrhagic fever and SARS are two examples of these diseases, but there are many other epidemics which also pose a danger. Dealing with these infectious diseases has thus become an urgent priority for this country, and this calls for enhancing the study both from basic and applied research, and furthermore, to concentrate greater attention to security, prevention and countermeasures.
We intend to analyze infection mechanisms and host cell responses with latest biological approaches; and explore basic development of protection strategies as well as biological prevention and protection measures. We also plan to focus on research on technological measures and practical applications of basic drug development. In addition, we will explore the methodologies of enantioselective synthesis for organic compounds which would protect against bio/chemical terrorism.
Needless to say, the same approach used to deal with infectious disease can also be applied to contending with bio/chemical terrorism. Thus, our research project outcomes can provide broad contributions not only to prevent infection, but also to enhance security of the population.